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Title: | A protocol for a prospective, multicentre observational study to determine if nonanaemic iron deficiency worsens postoperative outcome in patients undergoing elective surgery for resection of colorectal cancer: The NATO study. | Austin Authors: | Miles, Lachlan F ;Pac Soo, Vanessa;Braat, Sabine;Burgess, Adele N ;Heritier, Stephane;Smart, Philip J ;Tan, Nicole;Parker, Anna;Burbury, Kate L;Story, David A | Affiliation: | Department of Critical Care, Melbourne Medical School, The University of Melbourne, Melbourne, Australia. Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia. Department of Surgery, Melbourne Medical School, The University of Melbourne, Melbourne, Australia. Department of Epidemiology and Preventative Medicine, Monash University, Melbourne, Australia. Sir Peter MacCallum Department of Oncology, Melbourne Medical School, The University of Melbourne, Melbourne, Australia. |
Issue Date: | Feb-2023 | Date: | 2022-10 | Publication information: | Colorectal Disease 2023 | Abstract: | Preoperative absolute and functional iron deficiency anaemia is associated with poor postoperative outcomes in patients undergoing surgery for colorectal cancer. It is biologically plausible that "early", or "nonanaemic" iron deficiency may also be associated with worse postoperative outcomes in similar cohorts, albeit at lesser severity than that seen for anaemia. The evidence supporting this assertion is of low quality. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/32245 | DOI: | 10.1111/codi.16371 | ORCID: | 0000-0003-2044-5560 0000-0003-3120-9707 |
Journal: | Colorectal Disease | Start page: | 315 | End page: | 325 | PubMed URL: | 36238969 | ISSN: | 1463-1318 | Type: | Journal Article | Subjects: | anaemia colorectal cancer ferritins iron deficiency postoperative complications Preoperative Care/methods Anemia, Iron-Deficiency/complications Anemia/complications Colorectal Neoplasms/surgery |
Appears in Collections: | Journal articles |
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