Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/35051
Title: Exercise training initiated early during hospitalisation in individuals with chronic obstructive pulmonary disease is safe and improves exercise capacity and physical function at hospital discharge: A systematic review and meta-analysis.
Austin Authors: Lai, Yuin;Cavalheri, Vinicius;Sawyer, Abbey;Hill, Kylie
Affiliation: Curtin School of Allied Health, Faculty of Health Sciences, Curtin University, Perth, WA, Australia.
Allied Health, South Metropolitan Health Service, Perth, WA, Australia.
Melbourne School of Health Sciences, University of Melbourne, Grattan Street, Parkville, Victoria, Australia
Institute for Breathing and Sleep
Issue Date: Mar-2024
Date: 2024
Publication information: Respiratory Medicine 2024-03; 223
Abstract: Earlier reviews of exercise in people during exacerbation of chronic obstructive pulmonary disease (COPD) included studies where exercise training was initiated late during hospital admission or shortly following hospital discharge. Our question was: in adults hospitalised with an exacerbation of COPD, does initiating exercise training early during an admission versus not initiating exercise training during admission, change outcomes measured at discharge? Systematic review and meta-analysis. Database searches of PubMed, the Cochrane Library, PEDro and EMBASE conducted in December 2021 and updated in January 2024. Studies were included if they had at least one group that was prescribed exercise training within 48 h of hospital admission (experimental) and at least one group that received usual care which did not include prescribed exercise training (control). Outcomes included exercise capacity, physical function, adverse events and uptake of outpatient pulmonary rehabilitation programs. Ten studies (423 participants; mean FEV1 ranging from 26 % to 50 % predicted) were included. At discharge, compared to the control group, the experimental group demonstrated better exercise capacity (standardised mean difference (SMD) 0.58, 95 % confidence interval (CI) 0.32 to 0.83; five studies, moderate effect, low certainty evidence) and physical function (SMD -0.54, 95 % CI -0.86 to -0.22; four studies, moderate effect, low certainty evidence). No observed serious adverse events were reported. None of the studies reported uptake of pulmonary rehabilitation following discharge. In adults with an exacerbation of COPD, exercise training prescribed within 48 h of hospitalisation was safe and improved exercise capacity and physical function.
URI: https://ahro.austin.org.au/austinjspui/handle/1/35051
DOI: 10.1016/j.rmed.2024.107554
ORCID: 
Journal: Respiratory Medicine
Start page: 107554
PubMed URL: 38307320
ISSN: 1532-3064
Type: Journal Article
Appears in Collections:Journal articles

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