Please use this identifier to cite or link to this item:
https://ahro.austin.org.au/austinjspui/handle/1/33571
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DC Field | Value | Language |
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dc.contributor.author | Dalli, Lachlan L | - |
dc.contributor.author | Borschmann, Karen | - |
dc.contributor.author | Cooke, Shae | - |
dc.contributor.author | Kilkenny, Monique F | - |
dc.contributor.author | Andrew, Nadine E | - |
dc.contributor.author | Scott, David | - |
dc.contributor.author | Ebeling, Peter R | - |
dc.contributor.author | Lannin, Natasha A | - |
dc.contributor.author | Grimley, Rohan | - |
dc.contributor.author | Sundararajan, Vijaya | - |
dc.contributor.author | Katzenellenbogen, Judith M | - |
dc.contributor.author | Cadilhac, Dominique A | - |
dc.date | 2023 | - |
dc.date.accessioned | 2023-08-23T07:20:05Z | - |
dc.date.available | 2023-08-23T07:20:05Z | - |
dc.date.issued | 2023-10 | - |
dc.identifier.citation | Stroke 2023-10; 54(10) | en_US |
dc.identifier.issn | 1524-4628 | - |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/33571 | - |
dc.description.abstract | Fractures are a serious consequence following stroke, but it is unclear how these events influence health-related quality of life (HRQoL). We aimed to compare annualized rates of fractures before and after stroke or transient ischemic attack (TIA), identify associated factors, and examine the relationship with HRQoL after stroke/TIA. Retrospective cohort study using data from the Australian Stroke Clinical Registry (2009-2013) linked with hospital administrative and mortality data. Rates of fractures were assessed in the 1-year period before and after stroke/TIA. Negative binomial regression, with censoring at death, was used to identify factors associated with fractures after stroke/TIA. Respondents provided HRQoL data once between 90 and 180 days after stroke/TIA using the EuroQoL 5-dimensional 3-level instrument. Adjusted logistic regression was used to assess differences in HRQoL at 90 to 180 days by previous fracture. Among 13 594 adult survivors of stroke/TIA (49.7% aged ≥75 years, 45.5% female, 47.9% unable to walk on admission), 618 fractures occurred in the year before stroke/TIA (45 fractures per 1000 person-years) compared with 888 fractures in the year after stroke/TIA (74 fractures per 1000 person-years). This represented a relative increase of 63% (95% CI, 47%-80%). Factors associated with poststroke fractures included being female (incidence rate ratio [IRR], 1.34 [95% CI, 1.05-1.72]), increased age (per 10-year increase, IRR, 1.35 [95% CI, 1.21-1.50]), history of prior fracture(s; IRR, 2.56 [95% CI, 1.77-3.70]), and higher Charlson Comorbidity Scores (per 1-point increase, IRR, 1.18 [95% CI, 1.10-1.27]). Receipt of stroke unit care was associated with fewer poststroke fractures (IRR, 0.67 [95% CI, 0.49-0.93]). HRQoL at 90 to 180 days was worse among patients with prior fracture across the domains of mobility, self-care, usual activities, and pain/discomfort. Fracture risk increases substantially after stroke/TIA, and a history of these events is associated with poorer HRQoL at 90 to 180 days after stroke/TIA. | en_US |
dc.language.iso | eng | - |
dc.subject | fractures | en_US |
dc.subject | outcomes research | en_US |
dc.subject | population register | en_US |
dc.subject | quality of life | en_US |
dc.subject | stroke | en_US |
dc.title | Fracture Risk Increases After Stroke or Transient Ischemic Attack and Is Associated With Reduced Quality of Life. | en_US |
dc.type | Journal Article | en_US |
dc.identifier.journaltitle | Stroke | en_US |
dc.identifier.affiliation | Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia. | en_US |
dc.identifier.affiliation | The Florey Institute of Neuroscience and Mental Health | en_US |
dc.identifier.affiliation | Eastern Health, Box Hill, VIC, Australia | en_US |
dc.identifier.affiliation | Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia. | en_US |
dc.identifier.affiliation | Peninsula Clinical School, Central Clinical School, Monash University, Frankston, VIC, Australia (N.E.A.).;National Centre for Healthy Ageing, Frankston, VIC, Australia. | en_US |
dc.identifier.affiliation | Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC, Australia. | en_US |
dc.identifier.affiliation | Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia. | en_US |
dc.identifier.affiliation | Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia ;Alfred Health, Melbourne, VIC, Australia. | en_US |
dc.identifier.affiliation | Sunshine Coast Clinical School, School of Medicine, Griffith University, Birtinya, QLD, Australia. | en_US |
dc.identifier.affiliation | Department of Medicine, St Vincent's Hospital, Melbourne Medical School, University of Melbourne, VIC, Australia . | en_US |
dc.identifier.affiliation | School of Population and Global Health, The University of Western Australia, Perth, Australia . | en_US |
dc.identifier.affiliation | Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia. | en_US |
dc.identifier.doi | 10.1161/STROKEAHA.123.043094 | en_US |
dc.type.content | Text | en_US |
dc.identifier.orcid | 0000-0003-1449-9132 | en_US |
dc.identifier.orcid | 0000-0001-5364-2718 | en_US |
dc.identifier.orcid | 0000-0001-5531-0135 | en_US |
dc.identifier.orcid | 0000-0002-3375-287X | en_US |
dc.identifier.orcid | 0000-0002-4846-2840 | en_US |
dc.identifier.orcid | 0000-0001-5226-1972 | en_US |
dc.identifier.orcid | 0000-0002-2066-8345 | en_US |
dc.identifier.orcid | 0000-0001-5287-5819 | en_US |
dc.identifier.orcid | 0000-0001-8162-682X | en_US |
dc.identifier.pubmedid | 37581266 | - |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.openairetype | Journal Article | - |
crisitem.author.dept | The Florey Institute of Neuroscience and Mental Health | - |
Appears in Collections: | Journal articles |
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