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https://ahro.austin.org.au/austinjspui/handle/1/32881| Title: | Proton Beam Radiation Therapy for Oropharyngeal Squamous Cell Carcinoma. | Austin Authors: | Mendenhall, William M;Beitler, Jonathan J;Saba, Nabil F;Shaha, Ashok R;Nuyts, Sandra;Strojan, Primož;Bollen, Heleen;Cohen, Oded;Smee, Robert;Ng, Sweet Ping ;Eisbruch, Avraham;Ng, Wai Tong;Kirwan, Jessica M;Ferlito, Alfio | Affiliation: | Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA. Harold Alfonds Center for Cancer Care, Maine General Hospital, Augusta, ME, USA. Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA. Department of Head and Neck Surgery and Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Department of Radiation Oncology, Leuven Cancer Institute, University Hospitals Leuven, KU Leuven - University of Leuven, Leuven, Belgium.;Laboratory of Experimental Radiotherapy, Department of Oncology, University of Leuven, Leuven, Belgium. Department of Radiation Oncology, Institute of Oncology, Ljubljana, Slovenia. Olivia Newton-John Cancer Research Institute Department of Otolaryngology - Head and Neck Surgery and Oncology, Soroka Medical Center, Tel Aviv, Affiliated with Ben Gurion University of the Negev, Beer Sheva, Israel. Department of Radiation Oncology, The Prince of Wales Cancer Centre, Sydney, NSW, Australia. Radiation Oncology Department of Radiation Oncology, University of Michigan Medicine, Ann Arbor, Michigan, USA. Department of Clinical Oncology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China. Coordinator of the International Head and Neck Scientific Group, Padua, Italy. |
Issue Date: | Apr-2023 | Date: | 2023 | Publication information: | International Journal of Particle Therapy 2023 | Abstract: | To discuss the role of proton beam therapy (PBT) in the treatment of patients with oropharyngeal squamous cell carcinoma (OPSCC). A review of the pertinent literature. Proton beam therapy likely results in reduced acute and late toxicity as compared with intensity-modulated radiation therapy (IMRT). The extent of the reduced toxicity, which may be modest, depends on the endpoint and technical factors such as pencil beam versus passive scattered PBT and adaptive replanning. The disease control rates after PBT are likely similar to those after IMRT. Proton beam therapy is an attractive option to treat patients with OPSCC. Whether it becomes widely available depends on access. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/32881 | DOI: | 10.14338/IJPT-22-00030.1 | ORCID: | Journal: | International Journal of Particle Therapy | Start page: | 243 | End page: | 252 | PubMed URL: | 37169005 | ISSN: | 2331-5180 | Type: | Journal Article | Subjects: | cancer outcomes head and neck cancer oropharynx particle therapy |
| Appears in Collections: | Journal articles |
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