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Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/32103
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dc.contributor.authorSrinivasan, Ashish-
dc.contributor.authorDe Cruz, Peter P-
dc.contributor.authorSam, Melissa-
dc.contributor.authorToong, Catherine-
dc.contributor.authorvan Langenberg, Daniel R-
dc.date2023-
dc.date.accessioned2023-02-07T05:52:08Z-
dc.date.available2023-02-07T05:52:08Z-
dc.date.issued2023-05-
dc.identifier.citationJournal of Gastroenterology and Hepatology 2023-05; 38(5)en_US
dc.identifier.issn1440-1746-
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/32103-
dc.description.abstractThe optimal infliximab dose intensification strategy to address secondary loss of response (LOR) remains unclear. This study aimed to compare clinical and pharmacokinetic outcomes following (i) upfront infliximab re-induction with (ii) ongoing 6-weekly dose interval shortening (DIS), after the same number of doses.en_US
dc.language.isoeng-
dc.subjectAnti-tumor necrosis factoren_US
dc.subjectCrohn's diseaseen_US
dc.subjectDose intensificationen_US
dc.subjectSecondary loss of responseen_US
dc.subjectTertiary nonresponseen_US
dc.subjectTertiary responseen_US
dc.subjectTherapeutic drug monitoringen_US
dc.subjectUlcerative colitisen_US
dc.titleDose intensification strategy influences infliximab pharmacokinetics but not clinical response after the same number of doses.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleJournal of Gastroenterology and Hepatologyen_US
dc.identifier.affiliationDepartment of Gastroenterology, Eastern Health, Melbourne, Australia.en_US
dc.identifier.affiliationGastroenterology and Hepatologyen_US
dc.identifier.affiliationDepartment of Immunopathology, NSW Health Pathology Liverpool Hospital, Sydney, Australia.en_US
dc.identifier.doi10.1111/jgh.16133en_US
dc.type.contentTexten_US
dc.identifier.orcid0000-0001-5952-1570en_US
dc.identifier.orcid0000-0002-3399-7236en_US
dc.identifier.orcid0000-0003-3662-6307en_US
dc.identifier.pubmedid36692034-
local.name.researcherDe Cruz, Peter P
item.languageiso639-1en-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeJournal Article-
crisitem.author.deptGastroenterology and Hepatology-
crisitem.author.deptGastroenterology and Hepatology-
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