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Title: | Plasma Aβ42/40 ratio, p-tau181, GFAP, and NfL across the Alzheimer's disease continuum: A cross-sectional and longitudinal study in the AIBL cohort. | Austin Authors: | Chatterjee, Pratishtha;Pedrini, Steve;Doecke, James D;Thota, Rohith;Villemagne, Victor L ;Doré, Vincent ;Singh, Abhay K;Wang, Penghao;Rainey-Smith, Stephanie;Fowler, Christopher;Taddei, Kevin;Sohrabi, Hamid R;Molloy, Mark P;Ames, David;Maruff, Paul;Rowe, Christopher C ;Masters, Colin L ;Martins, Ralph N | Affiliation: | Macquarie Medical School, Macquarie University, North Ryde, New South Wales, Australia. School of Medical and Health Sciences, Edith Cowan University, Perth, Western Australia, Australia. Australian eHealth Research Centre, CSIRO, Brisbane, Queensland, Australia. Department of Psychiatry, University of Pittsburgh, Pennsylvania, Pittsburgh, USA. Macquarie Business School, Macquarie University, North Ryde, New South Wales, Australia. College of Science, Health, Engineering and Education, Murdoch University, Perth, Western Australia, Australia. The Florey Institute of Neuroscience and Mental Health School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, New South Wales, Australia. National Ageing Research Institute, Parkville, Victoria, Australia. Molecular Imaging and Therapy |
Issue Date: | Apr-2023 | Date: | 2022 | Publication information: | Alzheimer's & Dementia: the Journal of the Alzheimer's Association 2023; 19(4) | Abstract: | Plasma amyloid beta (Aβ)1-42/Aβ1-40 ratio, phosphorylated-tau181 (p-tau181), glial fibrillary acidic protein (GFAP), and neurofilament light (NfL) are putative blood biomarkers for Alzheimer's disease (AD). However, head-to-head cross-sectional and longitudinal comparisons of the aforementioned biomarkers across the AD continuum are lacking. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/31908 | DOI: | 10.1002/alz.12724 | ORCID: | Journal: | Alzheimer's & Dementia | PubMed URL: | 36574591 | ISSN: | 1552-5279 | Type: | Journal Article | Subjects: | Alzheimer's disease amyloid beta blood biomarkers brain amyloid beta diagnosis glial fibrillary acidic protein longitudinal monitoring neurofilament light p-tau181 single molecule array |
Appears in Collections: | Journal articles |
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