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Title: | Cerebrospinal fluid levels of fatty acid-binding protein 3 are associated with likelihood of amyloidopathy in cognitively healthy individuals. | Austin Authors: | Dhiman, Kunal;Villemagne, Victor L ;Fowler, Christopher;Bourgeat, Pierrick;Li, Qiao-Xin;Collins, Steven;Rowe, Christopher C ;Masters, Colin L ;Ames, David;Blennow, Kaj;Zetterberg, Henrik;Martins, Ralph N;Gupta, Veer | Affiliation: | IMPACT - The Institute for Mental and Physical Health and Clinical Translation School of Medicine Deakin University Geelong Victoria Australia. Department of Psychiatry University of Pittsburgh Pittsburgh Pennsylvania USA. The Florey Institute of Neuroscience and Mental Health Australian e-Health Research Centre CSIRO Health and Biosecurity Brisbane Queensland Australia. Department of Medicine The University of Melbourne Melbourne Victoria Australia. Molecular Imaging and Therapy PET National Ageing Research Institute Parkville Victoria Australia. Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology the Sahlgrenska Academy at the University of Gothenburg Gothenburg Sweden. School of Medical and Health Sciences Edith Cowan University Joondalup Western Australia Australia. |
Issue Date: | Dec-2022 | Date: | 2022 | Publication information: | Alzheimer's and Dementia 2022 | Abstract: | Fatty acid-binding protein 3 (FABP3) is a biomarker of neuronal membrane disruption, associated with lipid dyshomeostasis-a notable Alzheimer's disease (AD) pathophysiological change. We assessed the association of cerebrospinal fluid (CSF) FABP3 levels with brain amyloidosis and the likelihood/risk of developing amyloidopathy in cognitively healthy individuals. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/31805 | DOI: | 10.1002/dad2.12377 | ORCID: | Journal: | Alzheimer's and Dementia | Start page: | e12377 | PubMed URL: | 36479019 | Type: | Journal Article | Subjects: | Alzheimer's disease amyloid early diagnosis risk prediction screening |
Appears in Collections: | Journal articles |
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