Please use this identifier to cite or link to this item:
https://ahro.austin.org.au/austinjspui/handle/1/31382
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Quan, Stuart F. | - |
dc.contributor.author | Weaver, Matthew | - |
dc.contributor.author | Czeisler, Mark | - |
dc.contributor.author | Barger, Laura | - |
dc.contributor.author | Booker, Lauren | - |
dc.contributor.author | Howard, Mark | - |
dc.contributor.author | Jackson, Melinda | - |
dc.contributor.author | Lane, Rashon | - |
dc.contributor.author | McDonald, Christine F | - |
dc.contributor.author | Ridgers, Anna | - |
dc.contributor.author | Robbins, Rebecca | - |
dc.contributor.author | Varma, Prerna | - |
dc.contributor.author | Rajaratnam, Shantha | - |
dc.contributor.author | Czeisler, Charles | - |
dc.date.accessioned | 2022-12-13T04:01:58Z | - |
dc.date.available | 2022-12-13T04:01:58Z | - |
dc.date.issued | 2022-09-26 | - |
dc.identifier.citation | Preprints 2022, 2022090383 | en_US |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/31382 | - |
dc.description.abstract | Background: Medical comorbidities increase the risk of severe COVID-19 infection. In some studies, obstructive sleep apnea (OSA) has been identified as a comorbid condition that is associated with an increased prevalence of COVID-19 infection and hospitalization, but few have investigated this association in a general population. Research Question: In a general population, is OSA associated with increased odds of COVID-19 infection and hospitalization and are these altered with COVID-19 vaccination? Study Design: Cross-sectional survey of a diverse sample of 15,057 U.S. adults Results: COVID-19 infection and hospitalization rates were 38.9% and 2.9% respectively. OSA or OSA symptoms were reported in 19.4%. In logistic regression models adjusted for demographic, socio-economic and comorbid medical conditions, OSA was positively associated with COVID-19 infection (aOR: 1.58, 95%CI: 1.39-1.79) and COVID-19 hospitalization (aOR: 1.55, 95% CI: 1.17-2.05). In fully adjusted models, boosted vaccination status was protective against both infection and hospitalization. Boosted vaccination status attenuated the association between OSA and COVID-19 related hospitalization, but not infection. Participants with untreated or symptomatic OSA were at greater risk for COVID-19 infection; those with untreated, but not symptomatic OSA were more likely to be hospitalized. Interpretation: In a general population sample, OSA is associated with a greater likelihood of having had a COVID-19 infection and a COVID-19 hospitalization with the greatest impact observed among persons experiencing OSA symptoms or who were untreated for their OSA. Boosted vaccination status attenuated the association between OSA and COVID-19 related hospitalization. | en_US |
dc.subject | MEDICINE & PHARMACOLOGY | en_US |
dc.subject | General Medical Research | en_US |
dc.title | Associations Between Obstructive Sleep Apnea (OSA) and COVID-19 Infection and Hospitalization Among U.S. Adults | en_US |
dc.type | Journal Article | en_US |
dc.identifier.journaltitle | Preprints | en_US |
dc.identifier.affiliation | Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA; | en_US |
dc.identifier.affiliation | Francis Weld Peabody Society, Harvard Medical School, Boston, MA | en_US |
dc.identifier.affiliation | School of Psychological Sciences, Turner Institute for Brain and Mental Health, Monash University, Melbourne, Victoria, Australia | en_US |
dc.identifier.affiliation | Institute for Breathing and Sleep | en_US |
dc.identifier.affiliation | University Department of Rural Health, La Trobe Rural Health School, La Trobe University, Bendigo, Victoria, Australia | en_US |
dc.identifier.affiliation | Turner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australia; | en_US |
dc.identifier.affiliation | Department of Medicine, The University of Melbourne, Melbourne, Victoria, Australia | en_US |
dc.identifier.affiliation | Respiratory and Sleep Medicine | en_US |
dc.identifier.affiliation | Division of Sleep Medicine, Harvard Medical School, Boston, MA | en_US |
dc.identifier.affiliation | Faculty of Medicine, Monash University, Melbourne Australia | en_US |
dc.identifier.doi | 10.20944/preprints202209.0383.v1 | en_US |
dc.type.content | Text | en_US |
dc.type.austin | Journal Article | - |
local.name.researcher | McDonald, Christine F | |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.openairetype | Journal Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Institute for Breathing and Sleep | - |
crisitem.author.dept | Respiratory and Sleep Medicine | - |
Appears in Collections: | Journal articles |
Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.