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https://ahro.austin.org.au/austinjspui/handle/1/26245
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DC Field | Value | Language |
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dc.contributor.author | Miles, Lachlan F | - |
dc.contributor.author | Austin, Kristy | - |
dc.contributor.author | Eade, Alan | - |
dc.contributor.author | Anderson, David | - |
dc.contributor.author | Graudins, Andis | - |
dc.contributor.author | McGain, Forbes | - |
dc.contributor.author | Maplesden, Jacqueline | - |
dc.contributor.author | Greene, Shaun L | - |
dc.contributor.author | Rotella, Joe-Anthony | - |
dc.contributor.author | Dutch, Martin | - |
dc.date | 2021-04-15 | - |
dc.date.accessioned | 2021-04-19T05:58:46Z | - |
dc.date.available | 2021-04-19T05:58:46Z | - |
dc.date.issued | 2021-12 | - |
dc.identifier.citation | Emergency Medicine Australasia : EMA 2021; 33(6): 992-1000 | en |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/26245 | - |
dc.description.abstract | A large number of stimulant drug-associated deaths at music festivals in Australia were reported during the southern hemisphere summer of 2018-2019. This led to the prehospital deployment of healthcare professional-led critical care response teams. We aimed to describe the characteristics, clinical presentation, management and outcomes of music festival patrons with stimulant drug-induced serotonin toxicity managed using this model during the study period. We performed a retrospective observational study of patients presenting with stimulant drug-induced serotonin toxicity and/or drug-induced hyperthermia who presented between December 2017 and December 2019. Comprehensive follow-up data were collected for those patients who required hospital admission. Data included demographics, clinical features, management and disposition, hospital outcomes and laboratory data, stratified by severity of presentation. Forty-seven patients were included. Median age was 21.9 years (interquartile range 19.6-22.2). 3,4-Methylenedioxymetamphetamine was the most frequently reported agent ingested (32/47). After stratification, 13 of 47 patients were classified as mild, 20 of 47 as moderate and 14 of 47 as severe. Median presenting temperature in this latter cohort was 41.1°C (40.5-42.0°C). All severely ill patients required intensive care unit admission, with a median hospital stay of 4.63 days (interquartile range 2.08-8.36). End-organ complications were reported in 11 of 14 patients. No mortalities were reported. All patients (13/13) from the mild cohort and 15 of 20 patients from the moderate cohort were treated and discharged on-site. Severe illness was associated with a high incidence of end-organ impairment. A high proportion of patients without severe disease were able to be successfully managed at the event without transport to hospital. No deaths are reported in this series. | en |
dc.language.iso | eng | |
dc.subject | N-methyl-3,4-methylenedioxymetamphetamine | en |
dc.subject | drug-induced hyperthermia | en |
dc.subject | prehospital care | en |
dc.subject | serotonin toxicity | en |
dc.subject | MDMA | en |
dc.title | Characteristics, presentation and outcomes of music festival patrons with stimulant drug-induced serotonin toxicity. | en |
dc.type | Journal Article | en |
dc.identifier.journaltitle | Emergency Medicine Australasia : EMA | en |
dc.identifier.affiliation | Monash Toxicology Service, Monash Health, Melbourne, Victoria, Australia | en |
dc.identifier.affiliation | Victorian Poisons Information Centre | en |
dc.identifier.affiliation | Department of Emergency Medicine, St Vincent's Hospital, Melbourne, Victoria, Australia | en |
dc.identifier.affiliation | Department of Intensive Care, Western Health, Melbourne, Victoria, Australia | en |
dc.identifier.affiliation | Department of Intensive Care and Hyperbaric Medicine, Alfred Health, Melbourne, Victoria, Australia | en |
dc.identifier.affiliation | Clinical Services, St John Ambulance Australia, Melbourne, Victoria, Australia | en |
dc.identifier.affiliation | Department of Critical Care, The University of Melbourne, Melbourne, Victoria, Australia | en |
dc.identifier.affiliation | Department of Emergency Medicine, The Royal Melbourne Hospital, Melbourne, Victoria, Australia | en |
dc.identifier.doi | 10.1111/1742-6723.13778 | en |
dc.type.content | Text | en |
dc.identifier.orcid | 0000-0003-2044-5560 | en |
dc.identifier.orcid | 0000-0002-7423-2467 | en |
dc.identifier.pubmedid | 33858034 | |
local.name.researcher | Graudins, Andis | |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.openairetype | Journal Article | - |
crisitem.author.dept | Anaesthesia | - |
crisitem.author.dept | Victorian Poisons Information Centre | - |
crisitem.author.dept | Emergency | - |
crisitem.author.dept | Toxicology | - |
crisitem.author.dept | Emergency | - |
crisitem.author.dept | Toxicology | - |
Appears in Collections: | Journal articles |
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