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Title: | Massive Citalopram Overdose Associated with Recurrent Seizures and Bilateral Shoulder Dislocations. | Austin Authors: | Zoofaghari, Shafeajafar;Wong, Anselm Y ;Kiarasi, Pegah;Gheshlaghi, Farzad | Affiliation: | Department of Clinical Toxicology, Isfahan Clinical Toxicology Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran Department of Medicine and Radiology, Centre for Integrated Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, Victoria, Australia Emergency Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Victoria, Australia Department of Clinical Toxicology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.. Department of Clinical Toxicology, Isfahan Clinical Toxicology Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran Victorian Poisons Information Centre Toxicology |
Issue Date: | 8-Oct-2020 | Date: | 2020-07 | Publication information: | Journal of Research in Pharmacy Practice 2020; 9(3): 161-164 | Abstract: | Selective serotonin reuptake inhibitors (SSRIs) are widely used in the treatment of many types of mental disorders. Citalopram is commonly used as a new generation of SSRIs in this regard; however, unfortunately, its overdose is associated with seizure and heart disorders. The reported case in the present study indicated recurrent seizures, nonspecific ST-T changes, and prolonged QT interval due to the overuse of citalopram. The patient had bilateral anterior shoulder dislocation along with right proximal humerus fracture that was occurred during the seizure. The dislocation was initially reduced and then fixed. Moreover, the seizure was controlled with diazepam without any problems, and cardiac monitoring continued for 2 days. Massive citalopram overdose may be associated with recurrent seizures and QT prolongation. Complications postseizures, such as shoulder dislocations, should be examined for and managed appropriately. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/25751 | DOI: | 10.4103/jrpp.JRPP_20_24 | Journal: | Journal of Research in Pharmacy Practice | PubMed URL: | 33489987 | ISSN: | 2319-9644 | Type: | Journal Article | Subjects: | Citalopram seizure shoulder dislocation |
Appears in Collections: | Journal articles |
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