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https://ahro.austin.org.au/austinjspui/handle/1/25532| Title: | What is T+? A Gordian Knot of Tracers, Thresholds & Topographies. | Austin Authors: | Villemagne, Victor L ;Lopresti, Brian J;Doré, Vincent ;Tudorascu, Dana;Ikonomovic, Milos D;Burnham, Samantha;Minhas, Davneet;Pascoal, Tharick A;Mason, N Scott;Snitz, Beth;Aizenstein, Howard;Mathis, Chester A;Lopez, Oscar;Rowe, Christopher C ;Klunk, William E;Cohen, Ann D | Affiliation: | Department of Psychiatry, University of Pittsburgh, United States Department of Radiology, University of Pittsburgh School of Medicine Department of Neurology, University of Pittsburgh School of Medicine CSIRO Health & Biosecurity, Melbourne, Victoria, Australia Molecular Imaging and Therapy |
Issue Date: | 31-Dec-2020 | Date: | 2020-12-31 | Publication information: | Journal of Nuclear Medicine 2020; online first: 29 December | Abstract: | In this review we examine, in the context of the AT(N) framework, the available evidence as well as the potential alternatives on how to establish tau-positivity (T+) for multiple tau imaging tracers in order to come to a consensus for "normal" and "abnormal" tau imaging values that can be universally implemented in clinical research and therapeutic trials. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/25532 | DOI: | 10.2967/jnumed.120.245423 | Journal: | Journal of Nuclear Medicine | PubMed URL: | 33384320 | Type: | Journal Article | Subjects: | AT(N) framework Alzheimer s disease Biomarkers Molecular Imaging Neurology PET Tau imaging brain imaging |
| Appears in Collections: | Journal articles |
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