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Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/21581
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dc.contributor.authorBozaoglu, Kiymet-
dc.contributor.authorGao, Yujing-
dc.contributor.authorStanley, Edouard-
dc.contributor.authorFanjul-Fernández, Miriam-
dc.contributor.authorBrown, Natasha J-
dc.contributor.authorPope, Kate-
dc.contributor.authorGreen, Cherie C-
dc.contributor.authorVlahos, Katerina-
dc.contributor.authorSourris, Koula-
dc.contributor.authorBahlo, Melanie-
dc.contributor.authorDelatycki, Martin-
dc.contributor.authorScheffer, Ingrid E-
dc.contributor.authorLockhart, Paul J-
dc.date2019-08-01-
dc.date.accessioned2019-08-19T06:13:05Z-
dc.date.available2019-08-19T06:13:05Z-
dc.date.issued2019-08-01-
dc.identifier.citationStem cell research 2019-08-01; 39: 101516-
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/21581-
dc.description.abstractWe have generated and characterized seven human induced pluripotent stem cell (iPSC) lines derived from peripheral blood mononuclear cells (PBMCs) from a single family, including unaffected and affected individuals clinically diagnosed with Autism Spectrum Disorder (ASD). The reprogramming of the PBMCs was performed using non-integrative Sendai virus containing the reprogramming factors POU5F1 (OCT4), SOX2, KLF4 and MYC. All iPSC lines exhibited a normal karyotype and pluripotency was validated by immunofluorescence, flow cytometry and their ability to differentiate into the three embryonic germ layers. These iPSC lines are a valuable resource to study the molecular mechanisms underlying ASD.-
dc.language.isoeng-
dc.titleGeneration of seven iPSC lines from peripheral blood mononuclear cells suitable to investigate Autism Spectrum Disorder.-
dc.typeJournal Article-
dc.identifier.journaltitleStem cell research-
dc.identifier.affiliationDepartment of Neurology, Royal Children's Hospital, Melbourne, Australiaen
dc.identifier.affiliationFlorey Institute, Melbourne, Victoria, Australiaen
dc.identifier.affiliationMurdoch Children's Research Institute, Parkville, Australiaen
dc.identifier.affiliationBruce Lefroy Centre for Genetic Health Research, Murdoch Children's Research Institute, Melbourne, Victoria 3052, Australiaen
dc.identifier.affiliationVictorian Clinical Genetics Services, Victoria, Australiaen
dc.identifier.affiliationDepartment of Paediatrics, University of Melbourne, Parkville, Australiaen
dc.identifier.affiliationDepartment of Anatomy and Developmental Biology, Monash University, Clayton, Victoria 3800, Australiaen
dc.identifier.affiliationOlga Tennison Autism Research Centre, School of Psychology and Public Health, La Trobe University, Bundoora, Victoria, Australiaen
dc.identifier.affiliationDepartment of Medicine, Austin Health, The University of Melbourne, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationThe Walter and Eliza Hall Institute of Medical Research, Melbourne, Australiaen
dc.identifier.affiliationDepartment of Medical Biology, University of Melbourne, Melbourne, Australiaen
dc.identifier.doi10.1016/j.scr.2019.101516-
dc.identifier.orcid0000-0002-3160-2106-
dc.identifier.orcid0000-0002-2311-2174-
dc.identifier.pubmedid31415975-
dc.type.austinJournal Article-
local.name.researcherScheffer, Ingrid E
item.languageiso639-1en-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeJournal Article-
item.grantfulltextnone-
crisitem.author.deptEpilepsy Research Centre-
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