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https://ahro.austin.org.au/austinjspui/handle/1/13289| Title: | Surgical damage stimulates proliferation of dopamine uptake sites in normal mouse brain. | Austin Authors: | Howells, David William;Donnan, Geoffrey A ;Wong, J Y;Kaczmarczyk, S J;Chilcho, P J;Fabinyi, Gavin C ;Mendelsohn, Frederick AO | Affiliation: | Department of Neurology, Austin Hospital, Heidelberg, Australia | Issue Date: | 17-Sep-1993 | Publication information: | Brain Research; 622(1-2): 285-8 | Abstract: | To test the hypothesis that proliferation of host dopaminergic tissue in response to injury plays an important role in the response to intrastriatal grafting, we transplanted autologous adrenal medullary to striatum in normal C57-black mice and compared this procedure with transplantation of non-dopaminergic tissue (frontal cortex) or a non-cellular matrix (Gelfoam). [3H]Mazindol autoradiography revealed that all three protocols resulted in a marked proliferation of dopamine uptake sites 10 months after transplantation. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/13289 | Journal: | Brain Research | URL: | https://pubmed.ncbi.nlm.nih.gov/8242368 | Type: | Journal Article | Subjects: | Adrenal Medulla.transplantation Animals Brain.metabolism Cerebral Cortex.transplantation Corpus Striatum.surgery Dopamine.metabolism Gelatin Sponge, Absorbable Male Mice Mice, Inbred C57BL Reference Values Transplantation, Heterotopic.adverse effects |
| Appears in Collections: | Journal articles |
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