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https://ahro.austin.org.au/austinjspui/handle/1/13273| Title: | Serotonergic function in panic disorder: endocrine responses to D-fenfluramine. | Austin Authors: | Judd, F K;Apostolopoulos, M;Burrows, Graham D;Norman, Trevor R | Affiliation: | Department of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia | Issue Date: | 1-Mar-1994 | Publication information: | Progress in Neuro-psychopharmacology & Biological Psychiatry; 18(2): 329-37 | Abstract: | 1. Prolactin and cortisol responses to d-fenfluramine were measured in 16 patients with DSM-III-R panic disorder and 14 normal controls. 2. Patients showed a greater mean prolactin response than controls but the difference between groups was not statistically significant (P > 0.05, MANOVA). 3. No consistent differences were observed between patients and controls with respect to cortisol responses (P > 0.05, MANOVA). 4. The results do not support the hypothesis of hypersensitive post-synaptic serotonin receptors in patients with panic disorder. 5. Studies in larger groups are necessary to confirm the trend and to explore receptor subtype sensitivity. | Gov't Doc #: | 8208982 | URI: | https://ahro.austin.org.au/austinjspui/handle/1/13273 | Journal: | Progress in neuro-psychopharmacology & biological psychiatry | URL: | https://pubmed.ncbi.nlm.nih.gov/8208982 | Type: | Journal Article | Subjects: | Adult Female Fenfluramine.therapeutic use Hormones.blood Humans Hydrocortisone.blood Male Panic Disorder.blood.drug therapy.physiopathology Prolactin.blood Psychiatric Status Rating Scales Receptors, Serotonin.drug effects Serotonin.physiology |
| Appears in Collections: | Journal articles |
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