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Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/10445
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dc.contributor.authorLee, Sze Tingen
dc.contributor.authorScott, Andrew Men
dc.date.accessioned2015-05-15T23:53:44Z
dc.date.available2015-05-15T23:53:44Z
dc.date.issued2007-11-01en
dc.identifier.citationSeminars in Nuclear Medicine; 37(6): 451-61en
dc.identifier.govdoc17920352en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/10445en
dc.description.abstractThe importance of hypoxia in disease pathogenesis and prognosis is gathering increasing clinical significance and having a greater impact on patient management and outcome. Previous efforts to evaluate hypoxia have included the invasive assessment of hypoxia with immunohistologic and histographic oxygen probes. The emergence of new radiotracers has allowed noninvasive assessment of hypoxia, with the most extensively investigated and validated positron emission tomography radiotracer of hypoxia to date being (18)F-fluoromisonodazole ((18)F-FMISO). This review discusses the relevance and biology of hypoxia in cells and organ systems, and reviews the laboratory and clinical applications of (18)F-FMISO in oncology and noncancer disease states.en
dc.language.isoenen
dc.subject.otherAnimalsen
dc.subject.otherBrain Ischemia.metabolism.radionuclide imagingen
dc.subject.otherBrain Neoplasms.metabolism.radionuclide imagingen
dc.subject.otherCarcinoma, Non-Small-Cell Lung.metabolism.radionuclide imagingen
dc.subject.otherCell Hypoxiaen
dc.subject.otherFluorine Radioisotopesen
dc.subject.otherGlioma.metabolism.radionuclide imagingen
dc.subject.otherHead and Neck Neoplasms.metabolism.radionuclide imagingen
dc.subject.otherHumansen
dc.subject.otherLung Neoplasms.metabolism.radionuclide imagingen
dc.subject.otherMisonidazole.analogs & derivatives.chemical synthesis.diagnostic use.pharmacokineticsen
dc.subject.otherMyocardial Ischemia.metabolism.radionuclide imagingen
dc.subject.otherNeoplasms.metabolism.radionuclide imagingen
dc.subject.otherPositron-Emission Tomographyen
dc.subject.otherRadiopharmaceuticals.chemical synthesis.diagnostic use.pharmacokineticsen
dc.subject.otherStroke.metabolism.radionuclide imagingen
dc.titleHypoxia positron emission tomography imaging with 18f-fluoromisonidazole.en
dc.typeJournal Articleen
dc.identifier.journaltitleSeminars in nuclear medicineen
dc.identifier.affiliationCentre for PET, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.doi10.1053/j.semnuclmed.2007.07.001en
dc.description.pages451-61en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/17920352en
dc.type.austinJournal Articleen
local.name.researcherLee, Sze Ting
item.grantfulltextnone-
item.openairetypeJournal Article-
item.languageiso639-1en-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
crisitem.author.deptMolecular Imaging and Therapy-
crisitem.author.deptMolecular Imaging and Therapy-
crisitem.author.deptOlivia Newton-John Cancer Research Institute-
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